DPCstruct | MC26141

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)408 ± 79 aa
Standard deviation of domain lengths78.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.02
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.33
Pfam Score49.27
Assigned Pfam label(s) CL0023- PF04403- CL0375

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812UAF2 52-432 KHFNAKNREPFWVLLLVLVSYGYLIPGLVEVLFSFNLVFDTGTGGFFGIGPDSSFNHAPPTTETMLGLVRLLWETGSWLGAVLVVFY…
A0A7C1AY36 25-372 TVNQNIFVLIRSRLNQPGTLSLGSAGRTKLIPWLLLVSFVFNVIALIVPFLKIDTFLSSEKIYSLPHSVALMWHARLYAIALLILGF…
A0A6F9CGJ5 166-588 None
A0A7S2UC07 603-1097 None
A0A7R9WZN7 48-391 None
A0A2D8AT86 22-439 None
A0A4Q7KGL8 6-392 None
A0A1Q9C8N6 759-1223 None
A0A3S7X098 420-821 None
A0A3S4JAN9 51-419 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.