DPCstruct | MC26116

Metacluster Properties and Pfam Annotations

Number of structural domains105
Mean domain length (aa)156 ± 31 aa
Standard deviation of domain lengths30.66
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score72.75
Mean fraction of residues predicted as intrinsically disordered0.35
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)16.57
Pfam Score77.37
Assigned Pfam label(s) CL0023- CL0126- CL0063- PF06480- PF13396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X2JWE8 8-154 VLVIVIIGVIIFGLFSYLNGNGNMPKQLTYNQFTEKLEKGDLKTLEIQPQQNVYMVSGKTKNDEDYSSTILYNNEKELQKITDAAKK…
A0A1S4KLN9 133-237 MMTVALVTTLGILGLLAFNEMRYKEITWKEFVNAYLARGIVEKLEVINKKWVRVRLLPGNQIDGNNVLWFNIGSVDTFERNLENVQL…
A0A4S4EIQ9 270-387 None
A0A0E0GMT3 87-238 None
A0A535L668 1-117 None
T1GYF2 55-210 None
V5ID67 4-175 None
A0A260M2M0 7-157 None
A0A146H843 545-713 None
A0A6P5FSQ1 138-267 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.