DPCstruct | MC26085

Metacluster Properties and Pfam Annotations

Number of structural domains38
Mean domain length (aa)89 ± 5 aa
Standard deviation of domain lengths4.52
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score82.28
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)49.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2K1WW44 709-792 KDSRSMKLFKVALADFVKEVLKPSWQQGNMSKEAFKTIVKKTVDKVAGAMKSHQIPKSKVKIDHYIDSSQWKLTKLVMGYVDKY
A0A2K2APY8 35-117 ESKVLRHFRSVLIDFVKELLKPTWREGHLSEDAHNTIVKKTAEKVLSSLQPHQIPAAVESIKQFLSSSQPKMTKLVEGYVSKY
A0A6P6GBM5 708-798 None
A0A654ESE8 1-82 None
A0A4Y7KVF1 794-881 None
M0ZQH7 96-190 None
A0A6A3AT46 685-771 None
A0A2K2DJN9 872-958 None
A0A835JPU6 420-504 None
K4A7M1 492-575 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.