DPCstruct | MC25977

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)159 ± 21 aa
Standard deviation of domain lengths20.58
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score93.10
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)27.65
Pfam Score94.49
Assigned Pfam label(s) CL0020- CL0381

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7G5HYL0 154-302 MHDQALNLANQGVTINEIHNQFTVPESLSNEWFNRGYHGSVSHNVRGIINKYLGFFDMNPATLNKLSPADSAKRYVKLAGGSKAMLN…
A0A2D6BNH6 59-183 FVIGDETAALVKLPPHLAAEPTLRDHYHRLSWIVKGLYTRFAGWFGDDALEMIQHTPAAEAERMLALAGGAERVLQRGRAALAEGDA…
A0A379XVR2 102-301 None
A0A4U9CYM5 1-138 None
A0A1C3JIQ1 123-306 None
A0A7W0IYZ0 19-165 None
A0P017 195-358 None
A0A7W6E1I8 88-226 None
A0A370I2G5 53-196 None
A0A2D8IVC2 397-557 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.