DPCstruct | MC25975

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)105 ± 15 aa
Standard deviation of domain lengths14.58
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score83.88
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.08
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1J7I546 5-84 DIRTLFLDVDRFFKSYSRYCDFDRISSDLRVAEKESNTIVEKWPMRLIHQPGQEGAQEEFKVMLRSNFTGMERYLEWKKV
A0A2D5SWA2 31-119 HPADKTSGAFIQMVEARTIFCDFDDLFEKYMKEVGFDVAARMAGVVMKRKNTIVGEWPLRLRGGARTEEFDLLLASGHTGCERYVEW…
C4JQL0 412-494 None
F0XDS6 656-761 None
A0A423X0F2 308-416 None
A0A395HXZ3 256-357 None
A0A1S8A9N7 4-103 None
A0A0F4GLC9 580-679 None
A0A2L2TDE3 52-148 None
A0A6A5ZV30 80-190 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.