DPCstruct | MC25933

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)121 ± 13 aa
Standard deviation of domain lengths13.05
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score89.60
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)29.29
Pfam Score100.00
Assigned Pfam label(s) CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4C1V3S5 190-303 MKTKRMEAYICRTFKTVAADGLPIFTCRLASVETSAKPSLTMEKEKYKNAYFQITRGDYSPLLKKVNENLTKAIDYAANDNEKNMLR…
M7T154 34-153 YYPKNDVNESDIAMVSKILEQNSIYPENTRLWKAENGVDFEVLLASVETGEITKLPLPNEKGSVSIIPGDHSSDLRHVCAELVEASK…
A0A0F8V2X4 89-221 None
E2LCU7 96-218 None
A0A7G2CTP2 207-316 None
A0A2G5IB72 1-101 None
A0A4Y2LPP4 64-172 None
A0A1X7T4G1 1-132 None
A0A1X7T434 214-336 None
A0A168B720 2-115 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.