DPCstruct | MC25926

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)228 ± 55 aa
Standard deviation of domain lengths54.93
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score72.44
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)25.60
Pfam Score88.33
Assigned Pfam label(s) PF04652- PF09787- PF18097

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A397D5Y7 4-171 KIPATFKAVTPFIRRAEELDRDRSRPESQMVAYYCRQYAMELGIKLRNHDASDEASNYLLSLMEALELEMRSLPAHTHEEGRIICEN…
M7SGA0 5-244 IPAKIRQAGIVPFVLRASQLDAARPVISYWCRYWAVNQILSKQLHNVDQECLEFTTTLMDRLEQTKNEQAGNEAILDDAAGQVYVEQ…
A0A812IQP8 209-447 None
R1GXM5 1-281 None
A0A433QFB2 3-259 None
L1LB59 9-220 None
A0A0S7E7X0 849-1033 None
A0A2S4VP89 2-255 None
A0A177WGA6 360-623 None
E9G4D0 9-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.