DPCstruct | MC259

Metacluster Properties and Pfam Annotations

Number of structural domains178
Mean domain length (aa)185 ± 41 aa
Standard deviation of domain lengths41.28
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.46
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)29.71
Pfam Score98.49
Assigned Pfam label(s) CL0237- PF19276

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q3GDE6 50-243 CQVFNDPIHGSIELHPLLIKIIDTPQFQRLRFIKQLGGVYFVYPGASHNRFEHSIGVGYLAGKLAEALRSRQPELNITERDVLCVQI…
U2LEI3 23-253 SLPIASYHRILSADFPEFINKYVDLPILQRLSGIGLLCGTDWTPLYRNRFFYSRLDHSIGVALILWHFTHDQAETLAGLLHDVSTPV…
A0A397FLL1 5-227 None
A0A5M8P8T2 6-112 None
A0A378BDN0 2-235 None
A0A453DNC3 2-204 None
A0A1Q9CGN6 26-249 None
G0PHH4 6-214 None
A0A1D1Z3E0 11-212 None
A0A177WV99 2-184 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.