DPCstruct | MC2586

Metacluster Properties and Pfam Annotations

Number of structural domains49
Mean domain length (aa)132 ± 17 aa
Standard deviation of domain lengths16.54
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score86.60
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)19.51
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A556C4Q2 189-318 PAMYGSRYELGMSTTEAAKAIRADIKDAKTTGYLPNDLTYSVRKSSASAMSIEVQGLTNDQIYAPADDMEPAYLGRRHRPEAAELKD…
A0A523V9A1 3-145 RDFKGSKYAETKDLDLAEIAKLVRADIKAAVKAGDLPKGTKTSVRISRYSMGQSLTATITECPGLIVANPDRVRFDLDDPHGHTTLP…
A0A7W6BPA5 22-131 None
A0A1G9QZE2 25-148 None
A0A0F9BYQ2 4-130 None
M2AR65 79-235 None
A0A7X0DNZ3 48-189 None
A0A4R6RS65 160-337 None
T3D328 69-203 None
A0A1C2J497 1-122 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.