DPCstruct | MC25846

Metacluster Properties and Pfam Annotations

Number of structural domains76
Mean domain length (aa)192 ± 33 aa
Standard deviation of domain lengths33.37
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.53
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.90
Pfam Score95.12
Assigned Pfam label(s) CL0018- PF14144- CL0061

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A833V1V2 6-166 WTSTTENIFMWVGGWRPSAAFHLFHSKSGMQLEARLEEIIRGGAVKDLGDVSATQLQALDRLQRETVRAERLISEEAAEAQEALAAA…
A0A1Y1I4E5 31-254 LEAQRNADVLPQDVQPHVDLWNELGSAKAKAIEGDVLYMAAGLWQTPFERAFSWLGGVRPTIMFQLIYSQIGAQTSRSLAALLEGEE…
A0A445IUS6 468-667 None
A0A6J0PAJ7 2-169 None
A0A251T440 1-195 None
A0A166BZR8 1-170 None
A0A6D2J604 4-241 None
A0A4Y7LEX6 300-562 None
A0A835HDU7 12-201 None
A0A7J7M9S0 7-159 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.