DPCstruct | MC25834

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)111 ± 17 aa
Standard deviation of domain lengths17.27
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.88
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)42.57
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1U7Y7I3 1-94 MEMKHLSSIANDVICRCAQKLDTSVDKIVHEFEAGWEPEMEGYSRKLVEFCCSKALIDMCSELEETIDDGSFIRFTFDMMLAWEMPT…
A0A6J5XZ02 1-117 MANRLKHLSSIANDVVQSCALKLETPVEKLVEEFETTWKADETAPVGHNITATNNNNNSYGRKFVEFCSAKVLQTRDICKTIEEKIA…
A0A445F009 91-185 None
A0A287UCP5 1-147 None
A0A2U1PZQ3 1-104 None
A0A1D6Q5P6 2-140 None
A0A4S4E0X2 23-136 None
A0A540MBQ5 2-118 None
Q7X635 3-121 None
A0A1U7YGL5 1-96 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.