DPCstruct | MC25823

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)75 ± 8 aa
Standard deviation of domain lengths7.65
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score90.53
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)40.60
Pfam Score100.00
Assigned Pfam label(s) CL0213

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K7FMJ0 7-68 TPYKIGDPCSDCPDACDNGLCTNPCLYEDTYSLCPQLKEQYTCNNRFVLKYCVASCQCTTKI
A0A444TVE5 16-102 FGLQLIRGNHLSSLSTPYKKGAPCSSCEGHCKARKLCKNSCSYGDIWINCKELDFAFHNWLCNSKKTKQGLQRFRHCKATCLCKNKI
A0A7J7WUT7 292-360 None
E9ISB0 1-86 None
A0A0N7ZA67 367-452 None
A0A2K6L7K9 83-152 None
A0A402FFY7 220-290 None
A0A182QW82 320-401 None
A0A1D1VUF1 350-419 None
A0A0L7LEN1 108-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.