DPCstruct | MC25818

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)250 ± 40 aa
Standard deviation of domain lengths40.39
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score70.33
Mean fraction of residues predicted as intrinsically disordered0.49
Mean length-normalized TM-Score0.44
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)21.84
Pfam Score100.00
Assigned Pfam label(s) PF14075

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444TMH6 1-208 MTENRKELKLLKGSSESESEEEKGEQLEKGIENKIEEQIGENEEEICASNDNEANLSDDNDRESILPSDLPQDIVAVIDKLKEVGKN…
A0A2N1JD58 458-694 DTAAPESASTTPADKAEKKKNKYPIQPVHPDLQKRFDHLKTLVQRASFAVKTKFPPELKPPLIETAKLAVELDEYNENFFNYLPSIF…
A0A3P8FMS2 9-251 None
A0A177B2Z2 124-360 None
A0A6A4WQ01 260-509 None
E1B7L7 356-610 None
A0A183QVE1 153-395 None
A0A166HRK6 276-648 None
A0A1S3I8Q8 249-492 None
A0A1Y1NBW1 265-485 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.