DPCstruct | MC25817

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)427 ± 79 aa
Standard deviation of domain lengths78.84
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score67.07
Mean fraction of residues predicted as intrinsically disordered0.63
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)28.10
Pfam Score80.83
Assigned Pfam label(s) PF14641- PF14632

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H1C650 2-432 NSIPFNLHIPLDIRDFIVDDRANEAPTKAPRRIVHKGAALQQAQSIFGVDFDMSEFEAFRKGPAEGDEYSEESEPEYSDDEEATARP…
A0A388KCG4 4-411 AIRELELDEDDYALLEENQGFRRPREVVKEKKQLKRLKKAGRAQGEDGEQITGEVSGDDDDHEERGAGRTAEEEIKRSLFGDDEGVA…
A0A1A9WFV4 1-255 None
A0A1D6M791 100-582 None
U7PWQ2 16-575 None
A0A820AQZ2 85-608 None
A0A7R9A5I3 49-510 None
A0A6D2JBP6 23-473 None
A0A183NFC1 41-488 None
K7HUM5 56-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.