DPCstruct | MC25780

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)108 ± 15 aa
Standard deviation of domain lengths14.91
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.06
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)20.92
Pfam Score100.00
Assigned Pfam label(s) PF10947

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A448TT73 1-114 MAREVFLKNNMGVVKSGYVGFSWTVFFFGCFAPLFRGNFSWFLIMAFVGIVRVIAERLPPEYYASSNGQMWFSIIFIVIHLFFSFTY…
A0A372JUQ6 2-99 TERIYLRHPSQDETVAVGIGFSWPALLLGFIWALMKRLWGIAAFMLAVDLALGLIGLAGVSADLISLALSIVFAIYCGMRANDWHRR…
A0A6M1VS67 1-94 None
A0A344W9E2 24-161 None
G2KUA4 1-93 None
A0A1I6M0D5 5-107 None
A0A356FXE4 15-132 None
B6WXQ0 3-108 None
A0A0R1SFT1 16-105 None
A0A3M3MK52 1-111 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.