DPCstruct | MC25749

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)225 ± 34 aa
Standard deviation of domain lengths34.49
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score65.25
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)20.87
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V1CHT0 7-197 HAIGLQFLLSDVTVAQNTARQTLYLEDQFLPMKPCAARCIAYSTGGCGVDKLANVLGCPYAYCEKETGAPNDCYCRGDNQAPANSYL…
S8BQL8 13-265 ILSIIILINPTAVAQDPIPVIESYKITNALSYNYLRTCGLCCLGVGFCYDAQRLTNVLACTVNSCLCRRADISTSALSYISSCVNSA…
A0A2T2PBE3 3-241 None
A0A179FK83 1-195 None
A0A7J6JET7 4-232 None
A0A0U5GXE1 6-159 None
A0A7C8JFI9 7-249 None
A0A1L7WJB1 2-265 None
A0A1L7XD95 60-297 None
G0SA57 142-404 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.