DPCstruct | MC25745

Metacluster Properties and Pfam Annotations

Number of structural domains106
Mean domain length (aa)151 ± 26 aa
Standard deviation of domain lengths25.86
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.82
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)21.24
Pfam Score100.00
Assigned Pfam label(s) CL0317

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3B5JY16 50-201 LDRMEWTSNFAHHIKALECDDSWNLEFDDKIDPKNPDPGWRTFMWCSSAWFKCSGCKRSWPSNNVMVAFHMRLMDKEGTVKVKRFRQ…
S8A8Z3 87-230 KRKPKRRETPKIHYMFEKYHKKIEAQVQGILFSSVDREGDAEWETNIIGEFNCSNRRCKGRWHSGKIFTLIRKYNRADGQLGYNAQV…
A0A4U1FFQ1 16-174 None
A0A6P7ZC07 11-167 None
T5BSY1 90-238 None
A0A7J7YI69 5-133 None
A0A6A4VTR7 1-149 None
A0A818S279 33-185 None
H0XSS6 33-167 None
Q2HBV0 16-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.