DPCstruct | MC25727

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)454 ± 60 aa
Standard deviation of domain lengths59.56
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score70.28
Mean fraction of residues predicted as intrinsically disordered0.45
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)18.04
Pfam Score91.67
Assigned Pfam label(s) CL0123- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A367KWL2 6-352 IALEQSASIAEQLLQEFLKDNISEPRTEKLFYQAIETRSNHFGDALFLDPVSVISNTSSSKEKFDLELAVEKINLASFAHKAYKLED…
M7PKB1 2-464 EGQITEKKRSENYVDENHEMSGVDEDYSEAFRKKTKLKRELNVLNHETFTQNLNTTHEESHARLEDIQQELASEFHPDLSMLEHLPT…
M2LCG7 9-410 None
A0A5M3ZDN1 44-531 None
B0XYT1 1-534 None
A0A317XKN0 8-529 None
S9W2U6 1-483 None
A0A1Q8S4T8 13-445 None
A0A3N4K4G4 19-477 None
L8FM80 8-509 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.