DPCstruct | MC25725

Metacluster Properties and Pfam Annotations

Number of structural domains288
Mean domain length (aa)310 ± 69 aa
Standard deviation of domain lengths69.01
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score80.80
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)13.55
Pfam Score69.34
Assigned Pfam label(s) CL0192- CL0236- PF10505- PF04712

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A803R5J0 2-163 ATAYIRHEPWEMGVHKRNGVVYLDVHKLPERPQSDFERRRCYWGYCFESLATEDPRRTDGEGIHHVDANVEYCSVIKTKLGAHRILM…
M7NJD4 30-299 LDGLLLSLCEYERQHGFQRTFVDILTWRGILTRFLCTPFDRCTAWAVNIVRFQNTIFIEDHLETISLPTEQEARMRFWGYKFETLST…
A0A194UNA8 36-407 None
A0A6A5WY68 140-505 None
A0A7R9KWC7 292-654 None
A0A6G1IEX3 121-501 None
K7FR26 3-220 None
A0A6J0NZ75 25-298 None
U6KMJ9 187-558 None
A0A7S4SDP3 260-535 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.