DPCstruct | MC25712

Metacluster Properties and Pfam Annotations

Number of structural domains199
Mean domain length (aa)71 ± 14 aa
Standard deviation of domain lengths13.62
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score84.02
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)21.90
Pfam Score83.60
Assigned Pfam label(s) CL0039- CL0492- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3E0TRV1 4-73 VYLVEIDQQPIELYKLLKIADLVSGGGEAKLLIAEGYVLLNNEIELQKRKKVYDGDFIQLGDNIIEVQFV
A0A126ZZ95 16-90 QGSGAEETVEIREGTIRLGQLLKLASLVEDGVEAAELIRHGLVKVNGEIEERRGRQLGVGDSVEVNGQRVRLVPQ
H2G178 324-426 None
A0A2H0T9W2 1-58 None
A0A2W6V604 103-175 None
A0A820APQ6 1-68 None
A0A1V9Z361 514-615 None
A0A6L5C4H1 1-65 None
M7X241 249-351 None
A0A5B9P8B8 9-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.