DPCstruct | MC25706

Metacluster Properties and Pfam Annotations

Number of structural domains2220
Mean domain length (aa)295 ± 66 aa
Standard deviation of domain lengths66.42
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score85.51
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)18.29
Pfam Score93.84
Assigned Pfam label(s) CL0052- PF11807- CL0159- CL0570- PF00067

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M0D2S4 24-295 None
A0A6B0DWF7 95-418 None
A0A2R6EEB3 12-299 None
A0A1F6T3F3 262-500 None
A0A357BIX1 137-496 None
A0A3N4IG63 70-367 None
A0A3N4IJU1 487-806 None
A0A7R9YE74 314-712 None
A0A7C7QPQ5 58-350 None
A0A7C5J1S4 27-345 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.