DPCstruct | MC25645

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)262 ± 28 aa
Standard deviation of domain lengths27.79
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score78.35
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)20.33
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q2HF98 321-630 LDKSDLAAETLFAEWHATVAYLAAHIIPGQLELTLVCDVHYAGVETAKVVLDSLHLLPRLKNCHIRLCGVREPRLQQLAQDAVLRAR…
A0A0C2ILC9 45-319 DSTVAAAHVWGAALKTYPQDKPLLGLTVISDVGSVETAERVVAPLKRAVLPASRLRECTIRLGRRRRDFDLRAVAQQAILALTTGAD…
A0A6A6UF84 144-440 None
A0A319CXR8 46-295 None
A0A0C3CWW2 224-475 None
Q2H6T7 41-301 None
A0A1E3BEB0 21-252 None
U1HNP3 212-426 None
A0A7C8IRP6 112-399 None
A0A318ZCN3 563-802 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.