DPCstruct | MC25639

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)389 ± 65 aa
Standard deviation of domain lengths64.73
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.40
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.18
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A846DES7 3-288 TISASNVSGESQDISLENLETLEVNNSNISASTVDGTAGSINVNANESVQLTGEGGLNVAATGFGTAGTINVNTPQITIQDGAKISA…
A0A1Z4N1H5 1-463 MQEGSAIITVTYETANSGNIQIQSADIELSGFSLLNPVGVTSITTSTNGKGVAGDILINGNNLLISGGASLSSVTLGSGSTGQVMIR…
A0A3C0I5K7 306-731 None
A0A1V1P5S5 340-689 None
A0A3D4XTB6 1-374 None
A0A6P1KLA2 181-602 None
A0A7V9DZL5 19-319 None
A0A6I5Q8C8 1-353 None
A0A845ZPM3 1-444 None
A0A2H2XVU1 2-355 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.