DPCstruct | MC25568

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)176 ± 26 aa
Standard deviation of domain lengths25.82
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score89.02
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)31.93
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z7LY21 157-371 DNDSNYSKARLINNKGEIKDFSKFGLNKMDQLAIIRLLLKNKEELDDLTIEDYFSESFLKSNFWTFWRTMFAFENWHSLLELKLYMH…
A0A4S3JWC3 12-156 SPPDDIDTWILVWDCEAHSAFSHGIAPWNSVVASVTHDLHGLNHPRSLDRGPFNRHEAITVPVVQFLQSQESDFQFHTTVTDILLYP…
A0A1L9VPS8 36-254 None
E4HLF3 4-123 None
A0A0A2KQU0 114-299 None
U6F3L0 79-257 None
A0A395HXH4 18-201 None
A0A399H2W9 132-293 None
A0A094I7Y0 206-360 None
T0E1B7 7-183 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.