DPCstruct | MC25556

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)201 ± 13 aa
Standard deviation of domain lengths13.46
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score75.60
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)36.98
Pfam Score94.44
Assigned Pfam label(s) PF14744- PF14746

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B4HB68 213-417 RHFADKVLQLSPIDDHLPNQIIDQGIDVLQIMRNIHTFASSYAYNMNLQIFVEMQSKSKHLDIIGTRHVANSVQTHGTGIINTTVNF…
A0A182STT4 2-238 RAIVDRKYGIRLVEDQLPRTTAEDRRGPRGHGQDDDVLALMEDFETFIGSYGYDLHGQLFIERQQAAAAASGGGGSGGGPSSSGVLN…
A0A2H2JD85 1-202 None
K1PKW3 903-1108 None
A4I0W7 987-1188 None
A0A5N5SSL7 593-805 None
A0A817Z8E5 342-534 None
A0A329R7Z2 1-201 None
A0A2D8AM95 3-227 None
A0A6P4JX78 1-168 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.