DPCstruct | MC25535

Metacluster Properties and Pfam Annotations

Number of structural domains96
Mean domain length (aa)84 ± 14 aa
Standard deviation of domain lengths14.06
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.20
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)26.66
Pfam Score90.91
Assigned Pfam label(s) PF04296- PF17068

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W2A7S0 2-84 EPVRTCIGSRRRAPRSSLLRVVALSDGRVVADPKAVMPGRGAWLTPTVEAHDQAVKRRAYRRALRLDREPDTSAVRDYLEALS
A0A2S0KLJ9 4-84 KHIPTRMCIACREMRERQELFKLVKIDTGIVVDHLYKMDGRGTYICKDENCIKLAFAKGMLKRSLKAEVDPSLETELLDFI
A0A7C1GDH8 23-101 None
A0A832B359 2-78 None
K8F2W4 56-164 None
A0A538Q8X3 2-73 None
A0A516H0E3 27-121 None
A0A212DMT5 3-74 None
A0A7T6AQA1 1-64 None
A0A522N1L9 64-137 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.