DPCstruct | MC25527

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)80 ± 6 aa
Standard deviation of domain lengths5.65
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score87.77
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)45.11
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5K3EP37 1-77 MLCTFRCTSLLAGEKYPDGCGGGSVCFVRRKNQVYLQDVEEREDGGTPAIVESIRAGLVMQLKQAVTSEVIFAREEE
A0A822FC55 17-92 ILIAKKKLFTNRVPSECGGGTVNFVTRTNVEYVKDIETREEGGTPNILGAIRAGLAFHLKEAVGEKIIEKREEELF
A0A5K3EMP3 2-88 None
A0A1I7XH01 61-149 None
C3XWF9 193-266 None
A0A7X9BVU6 7-85 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.