DPCstruct | MC25478

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)133 ± 16 aa
Standard deviation of domain lengths15.69
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score78.28
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.27
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H8XWC5 49-188 DEGIMNGVNVQLTTPDSLAIDSYISLIRNQPCPVCSSTAQPLNAIVIGSVKSFIILTHYKKKLMIACPSCLQQANQRATASTALMGW…
A0A445N8G5 7-137 QPQSGQVHCRLCGGFPAVEATVRGHQGILIMMRSLSLKGPFCRNCGTAVWRDMTGKTLLQGWWSPLSLVLLTPFTLLWNLFVRVKIN…
A0A536DZP0 11-146 None
A0A1A3JBG0 1-130 None
A0A2T2UVM8 35-152 None
A0A7H8LRN9 1-105 None
A0A3M0ELR4 1-149 None
A0A426U097 1-147 None
A0A7K0W790 74-218 None
A0A1S1RAL8 1-98 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.