DPCstruct | MC25474

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)96 ± 5 aa
Standard deviation of domain lengths4.87
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score87.16
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)41.50
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1I1UKM3 248-346 GLCFAGPYAFVGLSKPRGSRTFGGLELEANLAARGAEPRCGLLVVDTRTGEVAHWLRLDGVVEELYDVAVLPGVRRPMALGLLSEEI…
A0A2S6R4Z0 1-101 MCGLAFINGFAIIGMSKCRENRTFSGLDLDDNLTKRKVEARCGVFVVDLSTGDLVQWVRLEGAVFEMYDVAVIPGVVRPMALGLRQE…
A0A068MVK2 246-339 None
A0A6M8VWB5 129-222 None
A0A1Z8RNP8 1-108 None
B5IQK8 510-606 None
A0A1T2L238 87-180 None
A0A5A5RCN9 260-359 None
A0A7Y5SLG2 142-230 None
A0A1H6Y7K0 194-286 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.