DPCstruct | MC25468

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)135 ± 11 aa
Standard deviation of domain lengths11.41
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score82.73
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)70.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S4CLG4 1-133 MLADKNAPNEKAWRQIEKMCLSTNASAIPVVPDSEGTEINPFSVDALAIFIFRVLHRANHPGNLDKSSPNAGCVLLMFYHLYEGKNR…
A0A453AW62 543-673 ADKNAPNEEVWRQIEDMCGMTKAAAVPVIPDSEGTDSNPFSLEALAVFMFRVLQRVNHPGNLDKASPNAGYILLMFYNLYDGKSRRE…
A0A446KF31 107-239 None
A0A2G3BAC0 437-572 None
A0A1U8FYA9 819-961 None
A0A287HEC1 672-805 None
A0A453HB59 42-167 None
A0A2P2M277 382-515 None
A0A438KNR4 1-150 None
M8ASH2 440-568 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.