DPCstruct | MC2546

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)125 ± 10 aa
Standard deviation of domain lengths10.27
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score94.29
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)48.46
Pfam Score100.00
Assigned Pfam label(s) PF06545

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376W1P5 148-277 IQAGYSVEQQREVFEFVASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPAQQVIGPMFAGYKP…
A0A1G8QR31 52-166 LVQTSFSTKDKVDVFNFVASSGYFSGPTWMALAKNAMDAAHNVEYRSILTTMARNGYEFGIRVSGLEGNQWFTGPAQVVVGPLFAGF…
A0A7X7IWT6 263-395 None
A0A6L8W9M2 378-487 None
A0A354U761 202-332 None
A0A0M0K0G8 853-979 None
A0A1G9AAJ4 289-413 None
A0A379WDI4 30-162 None
A0A2V6TAC4 774-910 None
A0A8B5W7B0 514-642 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.