DPCstruct | MC25454

Metacluster Properties and Pfam Annotations

Number of structural domains80
Mean domain length (aa)191 ± 35 aa
Standard deviation of domain lengths34.98
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.55
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)19.56
Pfam Score84.07
Assigned Pfam label(s) CL0021- CL0198- CL0214- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W6TUM6 1-138 MISSLRGVVLHSDADSVIVEVGGVGFSVAVPTDVARGLRAGDETLLHTNLVVREDALSLFGFAGRDELDTFTLLLSVSGVGPKSALG…
A0A6N7QVI6 22-228 REQGIIKVIKYKKDNFMIGILQKQNGEDITFKGNIFGIEKNEEIIFKGKWTEHIKYGKQFEVTKWERPIPKTKEKIISYLSSPFIKG…
B5Y8Y7 4-177 None
A0A1D2P7P5 16-180 None
A0A1V5RDL8 2-225 None
A0A5C9EI62 5-174 None
A0A6M3K1Q0 2-187 None
A0A3S6Z139 8-225 None
A0A1Y5EEG9 672-813 None
G9PKX7 1-212 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.