DPCstruct | MC25446

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)160 ± 17 aa
Standard deviation of domain lengths16.93
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score81.99
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)26.09
Pfam Score100.00
Assigned Pfam label(s) CL0344

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K1Z8X5 2-160 MRKLIKNFLTKRALRQWALAPIVIVTIGLGWKYYWLAFSVPMVILINMLSPLLSRGRFVCGNTCPRGAFFDRILRHFSQGKKIPGFL…
F5YGR7 37-186 WSWIITIVWITIANIWKPFGLYGFVCMFTPIGIALSGRGKMHCARICPRGSFIKVFTRRISLHLPKPAFMKKTAFRWALWGLMMGSF…
H0UNH5 4-149 None
A0A8B2XGD9 9-197 None
A0A3C1ILB0 9-188 None
A0A1I0EHG9 4-163 None
A0A4R7LCG9 2-161 None
A0A812U752 67-241 None
A0A2V3JJY0 57-182 None
U2DSC7 4-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.