DPCstruct | MC25401

Metacluster Properties and Pfam Annotations

Number of structural domains112
Mean domain length (aa)307 ± 74 aa
Standard deviation of domain lengths74.42
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score73.68
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)15.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z1NS01 3-176 TINSPQLLKTLKELVRFSPSESLDFDTQVSYDSPYNLLHHHRAELLEYKKTSADETALEHIDLLLLFLASEASDKGRVATKLIASGL…
A0A6A6W782 101-430 KSDKKLSTGSMPTAESYPVPFMPLAPGSMPPSFPPSMPPPPSCGAFDFNAPSADESGNKEPSPNSEADFDVKHLYAFGRCICSQCVF…
A0A4Y8CSE5 13-303 None
A0A5N6U119 10-214 None
C9SU39 60-422 None
J3PFG7 44-322 None
A0A0C3D8M7 208-535 None
A0A4Q7K933 4-228 None
A0A2J6TN52 70-259 None
T0L8H4 398-730 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.