DPCstruct | MC254

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)95 ± 7 aa
Standard deviation of domain lengths7.01
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score85.35
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)25.96
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z1NEF5 2-92 HVEASGVATFRVNATGQKVSVSASDLEWDCQGDGERNMGPELIHTADFDISGHTVTWSIWEYPVGVENHSDTHVPDGITLVADIDYG…
A0A1G3JQ48 3-99 TIYSRGIARIRHATTGEIFTIAADELEWAEFAADERQMGTEIGYSAEIEHPSLGTISWELWEYPVGAENMRETHTNGHVLIENIDFG…
A0A1C3RHK0 2-103 None
R6G3A6 1-97 None
A0A841LKE4 2-94 None
A0A8B2C4M0 1-85 None
A0A1R3T5I7 370-464 None
A0A6P0V8A7 1-99 None
A0A077Y2A4 321-420 None
A0A1Y5T5D2 2-96 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.