DPCstruct | MC25397

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)78 ± 9 aa
Standard deviation of domain lengths8.68
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.53
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.92
Mean intra-cluster sequence similarity (%)65.94
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A8A9AWS7 1-60 MTVYVSDEELLALEHARLELRGEHGLAVDRGRVVREAIAIVLDDLEEHGGDSPLVRRLRE
A0A0K3BLU5 9-77 QKHDTKITVYVSDEELLALEHARLALRGKHGLAVDRGRVVREAIAVLLADLDEYGEESMLVRRLRQENG
A0A4Q8CB47 193-273 None
A0A255EPA5 1-84 None
A0A384HXY7 119-195 None
A0A1E7K3L4 154-224 None
A0A6I4MH47 73-146 None
A0A160VNN6 1-67 None
S2W2C1 37-116 None
A0A852ZNX3 337-432 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.