DPCstruct | MC2539

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)117 ± 17 aa
Standard deviation of domain lengths17.20
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score94.07
Mean fraction of residues predicted as intrinsically disordered0.43
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.45
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0B8P0S7 52-166 NNEYTNYEYLFAHQGKSMTADDVKKAQAAHGVTVVEIVKKNGQWVVDKSGERNRRITANTEMMLTGPAAGHALLKTQADASGTKVLG…
A0A378QYR8 32-143 LANDVRREIHVHGVSVAEVKRTPTGYELIKDSPFNKRYTSGTPARLSGVAKGSEFVKTRLDPKGLLSVGINNQCGAGLSPWGTYLTT…
A0A285VPN1 222-319 None
A0A508ZBJ5 113-243 None
A0A6G3VBX0 77-206 None
A0A522DD55 159-251 None
A0A774NA18 68-194 None
A0A379Y155 15-141 None
A0A4R4GZD1 1-111 None
A0A164YZB5 2-99 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.