DPCstruct | MC25361

Metacluster Properties and Pfam Annotations

Number of structural domains144
Mean domain length (aa)166 ± 24 aa
Standard deviation of domain lengths24.17
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.13
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)17.00
Pfam Score81.51
Assigned Pfam label(s) CL0431- PF10240- CL0066

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C8V5W2 3-138 YLQSIDVRYGEDPSSEPSDGIHTVDGTNADINAGFGGDFVWLVPRYNSNAANAVSNIRIIIQGDPDSAYVDLAKGAGGDYRYLRLER…
A0A6A5A901 172-348 DSDEDENADDDDAPPTPLPITDLVVVFSGDVTPEDFEKIEKSPSGIKADLNRGRRGQFVYLCQKREIPSSYGYKRPPISDIILIYPE…
A0A654HIH5 3-139 None
A0A6A3T3P2 154-323 None
A0A0K0E693 38-224 None
A0A1L9WMM2 349-492 None
A0A0C2J764 27-196 None
A0A7N8XYW5 5-155 None
A0A416IGT4 29-215 None
A0A433Q995 88-260 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.