DPCstruct | MC25355

Metacluster Properties and Pfam Annotations

Number of structural domains14
Mean domain length (aa)180 ± 17 aa
Standard deviation of domain lengths17.24
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score85.47
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)34.00
Pfam Score100.00
Assigned Pfam label(s) PF18934

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376RYA1 300-497 AMALAQLRGHTLPLRTDWLDALAGSLIKEALNAPLPWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVTCELERTA…
A0A376KR64 1-174 MAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPLPWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVT…
A0A376U6X3 122-316 None
A0A6I1YKG1 370-524 None
A0A066Z0L2 322-488 None
A0A354PHK8 2-189 None
A0A535E5U7 210-395 None
A0A7X6KGC2 15-169 None
A0A4Q3X6P9 97-288 None
A0A4D4L8W0 177-328 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.