DPCstruct | MC25354

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)126 ± 28 aa
Standard deviation of domain lengths27.54
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score93.33
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)40.04
Pfam Score100.00
Assigned Pfam label(s) CL0108

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3S4FYF4 62-210 VFDTSFHQTLAPEAYLYGLPWEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKNSGLIVAHLGNGASICAVRNGQSVDTSMGMTP…
A0A376KQ87 186-274 EELNIITCHLGNGGSVSAIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGLLGLTEVTSDCRY…
A0A841JRH6 150-298 None
A0A438N6D0 155-311 None
A0A378AXI9 97-199 None
B4RI48 149-289 None
A0A2X3J4X5 103-196 None
A0A0F2IYR3 80-226 None
A0A7Y5M7C0 1-102 None
A0A447N887 7-148 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.