DPCstruct | MC25351

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)168 ± 18 aa
Standard deviation of domain lengths18.40
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score96.47
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)45.50
Pfam Score100.00
Assigned Pfam label(s) CL0124

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H3MAT1 154-331 GKNLLFTGNNGEVVLQNSVNQGGGYLQFAGDYRVSALNGQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNIGGL…
A0A376KIR9 18-185 VSGGGELTLKQDTDLGIGGLIFDKNQTYKVSGKDKSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSGTLDVKTAQGNNLKTGNGTV…
A0A4U8TH89 12-183 None
A0A378NFS1 341-518 None
A0A378NJC0 359-536 None
A0A378F342 303-486 None
A0A6G3I6H7 2-142 None
A0A2X5PFE9 327-483 None
A0A243V4M1 260-444 None
A0A1V4AYF1 1-182 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.