DPCstruct | MC25322

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)191 ± 33 aa
Standard deviation of domain lengths32.92
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score78.90
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)25.69
Pfam Score100.00
Assigned Pfam label(s) PF05983

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I0YMA0 22-184 FPPPPAFYKLYGTSADGSEVPAPPPPPPPVEGEYQLFGELYTTEDGIPPLTVRQLFTVNAQGLLDFKGELRRLNKELLFTFLDLLDC…
A0A4P9ZKI3 6-188 ISALYPPPPIYYKYFTKSNLDKFKALDDPALITGELKLQVPPEIPQSAHYRGYGSVWSLETKIPSLKSLGFTQLYQDEDEIITSKTK…
A0A1R2CEK5 3-156 None
A0A7J7QMN1 6-181 None
U6K0Z9 69-247 None
A0A2P5XWF3 3-138 None
A0A0M8MJX1 1-259 None
A0A0V0JCC7 13-206 None
A0A5N3W492 10-188 None
A0A6P6S562 37-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.