DPCstruct | MC25305

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)138 ± 9 aa
Standard deviation of domain lengths8.94
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score80.12
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.83
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)44.75
Pfam Score100.00
Assigned Pfam label(s) CL0456

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2S7QB94 2-146 TRILNQPMNATTSYIPGSSSYPKCASEMIMLFWEITQCNKRFRSFIIDTDRSHDFVILILFYSLEYRLDASKQGIVRMCVFILQTLS…
A0A833ZHV3 137-271 QTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILYFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNK…
A0A098VSX6 181-316 None
A0A5K3FAR7 331-458 None
A0A162N2T2 600-747 None
A0A820KDM8 11-129 None
S3CHD4 345-492 None
A0A0R3Q957 47-192 None
A0A1V6QFX9 347-487 None
A0A842ZGA0 100-235 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.