DPCstruct | MC25286

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)349 ± 53 aa
Standard deviation of domain lengths53.18
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score80.67
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.62
Pfam Score100.00
Assigned Pfam label(s) PF14750

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183HH77 1-248 MRFMRLLQKSTLHEQIQAMNAIVHAMVIALNPSSPVPFVNGAVAIWKRLENVVPRSLCEATVCAWSTDELNHDMLIEQPLFLFRCDE…
A0A3R7LSY6 14-419 VLDRLMRMPPHQVWPLAAPITASIKCLLQPGVPRKVLDTYRQVWMRLNSLFPRRLWAMSVEGLQPEQPQSKLRKALTEDDIILDPLY…
F0WBI7 720-1110 None
A0A1S8W8G5 631-884 None
A0A7R9B1S8 25-427 None
E5QCH1 782-1155 None
U9SL78 352-668 None
A0A3P7EFB2 228-576 None
A0A6V7UD18 397-744 None
A0A0R3RMK8 2-344 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.