DPCstruct | MC25275

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)144 ± 18 aa
Standard deviation of domain lengths17.71
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score75.97
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)30.78
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S4LXH5 531-672 NFAESSRPRRGFKESLKTKNTKIGRPRTKKATVAQRMNWMQPHIFEQIDAATKATGYPWRPVDIVQRLQRSNPRVFANLKHQRLSEW…
A0A409YTK1 30-163 NRKPQGRKKKNGPRPAKYHNWLTPFCWTQIVMVTKKVGWSASDIANGLKKLSPVVFGGINRNTIEGWIDRSGLKPKWKDSVLTRVRK…
A0A5E3XB60 135-291 None
A0A4Z0A593 382-522 None
A0A4Y9ZFH0 262-449 None
A0A2H3CMA3 14-143 None
A0A060T017 170-337 None
A0A074SDA4 192-327 None
K5XHG8 365-501 None
A0A409YJ76 565-733 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.