DPCstruct | MC25273

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)85 ± 11 aa
Standard deviation of domain lengths11.05
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.41
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)36.71
Pfam Score100.00
Assigned Pfam label(s) CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1D7VHG3 1-83 MAYESSVPYRAGTEGYTSFRIPAVVRARSGTVLALAEGRVSSTADRGDLDLVRKRSTDGGRTWGPLRVVARNGTATAGNPPRE
E1M5K0 36-121 LEKKLPEGAEITDKKDVFEAGKNGQSNPDGINSYRIPALLKTDKGTLIAGADERRLHHYDWGDIGMVVKRSEDQGQTWGDRITLTN
A0A4R2HZS9 83-147 None
A0A4T2GLE3 151-250 None
A0A139M9P0 325-417 None
A0A4W5LDX7 58-133 None
A0A137QJF9 28-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.