DPCstruct | MC25198

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)93 ± 8 aa
Standard deviation of domain lengths8.20
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score83.91
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)51.08
Pfam Score100.00
Assigned Pfam label(s) CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q0IRB2 1-87 LAFSLTLDSVEITSLDFVAPDEEVFDYWTDGINALLGNKMTSKEADNDLETLLSMEIKIRLLDAEGVEIPHHPPEVPEEPRNYDFNF
Q5FVI2 1-103 MKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPP…
A0A6F9CQH6 252-354 None
A0A7E6EIB2 66-144 None
A0A7R8HDV3 118-207 None
A0A2P8Y6L4 921-1006 None
A0A6P9AF91 853-941 None
A0A6A4TE37 896-991 None
A0A315V856 205-306 None
L5M970 125-227 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.