DPCstruct | MC25189

Metacluster Properties and Pfam Annotations

Number of structural domains71
Mean domain length (aa)180 ± 30 aa
Standard deviation of domain lengths29.80
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.44
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.53
Mean intra-cluster sequence similarity (%)21.61
Pfam Score100.00
Assigned Pfam label(s) CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J2YLS3 1-145 MATYLFVENGEIIPITRYGNVDKFIGTMKKVYDDASKGSKSKAKLRLASALRYVKFSFLRKHVWRVLREGSYEALGDLQRRSILLSA…
A0A550GBZ8 14-191 VSDFYPVPVVVPVSKAVGALKDKRYVEFTAHPHCGMATFVFVEEGKLKPVTRYGNIEKFRGSLEKVYLDAAKGSKSKAKLRLVGSAR…
A0A535VLP0 2-176 None
A0A523DUL9 222-412 None
A0A497HPL9 178-367 None
A0A7C0XNR2 1-111 None
A0A1W9WAM9 74-244 None
A0A645J7D2 12-134 None
A0A2J4JFQ2 281-469 None
A0A2V8NSG9 2-169 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.