DPCstruct | MC25176

Metacluster Properties and Pfam Annotations

Number of structural domains267
Mean domain length (aa)141 ± 26 aa
Standard deviation of domain lengths25.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)33.30
Pfam Score73.59
Assigned Pfam label(s) PF00200- CL0750- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1BMD3 199-379 None
A0A4Y2PUG3 641-845 None
A0A0L0T6S2 38-164 None
A0A534Q6D5 10-143 None
A0A803Y3Y6 538-692 None
A0A1I8HA77 53-167 None
A0A098VR72 134-277 None
A0A1U7TMZ8 246-379 None
A0A1A6HT79 56-196 None
A0A1Y3EWG3 187-330 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.