DPCstruct | MC25176

Metacluster Properties and Pfam Annotations

Number of structural domains267
Mean domain length (aa)141 ± 26 aa
Standard deviation of domain lengths25.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score81.35
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)33.30
Pfam Score73.59
Assigned Pfam label(s) PF00200- CL0750- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1EKQ5 7-102 CCDKNTCKFTRNAKCASGLCCNLNTCQLKKNSLCREAAGECDVEEVCDGASNHCPVDRHVNNTTPCQVGGGGFCFDGECNSHDKACQ…
A0A2I2YYD5 336-482 EDFAHFISKQKSQCLHNQPRLDPFFKQQAVCGNAKLEAGEECDCGTEQDCVLIGETCCDIATCRFKAGSNCAEGPCCENCLFMSKER…
A0A1B0AIJ0 67-238 None
A0A2I3M3V3 371-518 None
T1F641 234-411 None
T1ENU0 102-273 None
A0A6J3EK86 629-779 None
I8U2E9 675-831 None
A0A811LGU7 299-441 None
A0A498LQC5 385-531 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.